Awarded the Nobel Prize in Physiology or Medicine — for their discoveries concerning peripheral immune tolerance.
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Shimon Sakaguchi is a Japanese immunologist. He is a distinguished professor at Osaka University and a professor emeritus at Kyoto University.
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science · Japanese immunologist (born 1951) · physician · university teacher · immunologist · biologist · also Shimon Sakaguchi, Sakaguchi Shimon, Sakaguchi
Born 19 January 1951 · Q17502433
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Awarded the Nobel Prize in Physiology or Medicine — for their discoveries concerning peripheral immune tolerance.
MarketWatch: RegCell Scientific Founder and Board Member Dr. Shimon Sakaguchi Awarded Nobel Prize in Physiology or Medicine
The Conversation: Nobel laureate Shimon Sakaguchi on his immune system breakthrough – and the treatments he hopes it will unlock
Awarded Nobel Prize in Physiology or Medicine (2025).
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Was jointly awarded the Nobel Prize in Physiology or Medicine with Mary E
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Awarded Robert Koch Prize (2020).
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Awarded Paul Ehrlich and Ludwig Darmstaedter Prize (2020).
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Awarded Order of Culture (2019).
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Published “Global surveillance of trends in cancer survival 2000–14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries” in The Lancet — cited 4,344 times.
Awarded Crafoord Prize (2017).
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Awarded Clarivate Citation Laureates (2015).
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Awarded Canada Gairdner International Award (2015).
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Published “Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota” in Nature — cited 2,606 times.
Published “FOXP3+ regulatory T cells in the human immune system” in Nature Reviews Immunology — cited 2,080 times.
Awarded Keio Medical Science Prize (2008).
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Published “CTLA-4 Control over Foxp3 <sup>+</sup> Regulatory T Cell Function” in Science — cited 2,576 times.
Published “Regulatory T Cells and Immune Tolerance” in Cell — cited 4,537 times.
Published “Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self” in Nature Immunology — cited 2,046 times.
Published “Formation of dense partonic matter in relativistic nucleus–nucleus collisions at RHIC: Experimental evaluation by the PHENIX Collaboration” in Nuclear Physics A — cited 2,621 times.
Awarded William B. Coley Award (2004).
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Published “N<scp>aturally</scp>A<scp>rising</scp>CD4<sup>+</sup>R<scp>egulatory</scp>T C<scp>ells for</scp>I<scp>mmunologic</scp>S<scp>elf</scp>-T<scp>olerance and</scp>N<scp>egative</scp>C<scp>ontrol of</scp>I<scp>mmune</scp>R<scp>esponses</scp>” in Annual Review of Immunology — cited 2,575 times.
Published “Control of Regulatory T Cell Development by the Transcription Factor <i>Foxp3</i>” in Science — cited 6,656 times.
Sakaguchi's group demonstrated the importance of FOXP3 in the development and function of regulatory T cells
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Published “Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases” in The Journal of Immunology — cited 4,867 times.
Worked at Riken as an investigator of the Japan Science and Technology Agency
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Also received a PhD degree from Kyoto University
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From the Faculty of Medicine at Kyoto University
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Born 1951-01-19.
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