“All you need is enough test tubes, sufficient money, dedication, and hard work. ... and one more thing, you have got to be able to put up with endless failure.”
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Hideyo Noguchi , also known as Seisaku Noguchi , was a Japanese bacteriologist at the Rockefeller Institute during its foundation under Simon Flexner and known for his work on syphilis and contributing to the long term understanding of neurosyphilis.
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science · Japanese bacteriologist (1876–1928) · physician · microbiologist · pathologist · also Hideyo Noguchi, Hydeo Noguchi, Seisaku Noguchi, Noguchi Hideyo, Noguchi Seisaku, Noguchi
Born 9 November 1876 · Died 21 May 1928 · Q356114
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“All you need is enough test tubes, sufficient money, dedication, and hard work. ... and one more thing, you have got to be able to put up with endless failure.”
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Published “The 2021 WHO Classification of Lung Tumors: Impact of Advances Since 2015” in Journal of Thoracic Oncology — cited 1,369 times.
Published “The 2015 World Health Organization Classification of Lung Tumors” in Journal of Thoracic Oncology — cited 3,759 times.
Published “Comprehensive genomic profiles of small cell lung cancer” in Nature — cited 2,065 times.
Published “Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression” in Cell — cited 2,948 times.
Published “Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens” in Nature — cited 1,822 times.
Published “Guidelines for the use and interpretation of assays for monitoring autophagy” in Autophagy — cited 2,928 times.
Published “Everolimus in Postmenopausal Hormone-Receptor–Positive Advanced Breast Cancer” in New England Journal of Medicine — cited 2,444 times.
Published “International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma” in Journal of Thoracic Oncology — cited 3,874 times.
The conference venue was moved from Tokyo to Yokohama as another way of honoring the man after whom the prize was named
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Noguchi's face was featured on the 1000 yen note
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Published “Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40” in Nature — cited 1,367 times.
Published “The Belle detector” in Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment — cited 1,343 times.
Published “A New Quick-Response and High-Efficiency Control Strategy of an Induction Motor” in IEEE Transactions on Industry Applications — cited 2,643 times.
The Instituto Nacional de Salud Mental (National Institute of Mental Health) "Honorio Delgado – Hideyo Noguchi" was founded with founds of the Peruvian Government and the JICA (Japan International Cooperation Agency) in
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The Noguchi Memorial Institute for Medical Research (NMIMR) was founded with funds donated by the Japanese government at the University of Ghana in Legon, a suburb north of Accra
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Hans Zinsser, a personal friend of Noguchi, reluctantly said it had not been successful
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And made a career for herself, becoming professor at the North Western University
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Died 1928-05-21.
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The Japanese government awarded Noguchi the Order of the Rising Sun, Gold and Silver Star, which represents the second highest of eight classes associated with the award
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Awarded doctor honoris causa from the University of Paris (1925).
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Association of American Physicians granted him its prized Kober Medal for this discovery
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Noguchi had attempted creating passive and active immunity for Rocky mountain spotted fever
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Laboratory Diagnosis of Syphilis, which aided in the diagnosis and treatment of the disease
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Was elected as a member of the American Philosophical Society
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Awarded honorary degree presented by National University of San Marcos (1920).
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Awarded John Scott Award (1920).
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Noguchi's health had declined
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Suggests the name of the new genus Leptospira meaning slim spiral
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Awarded Imperial Prize of Japan Academy (1915).
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But it could have progressed to neurosyphilis, prone to personality changes
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Whom he met for a single time after he returned from Copenhagen
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Told his family that he did not plan to return to Japan
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Noguchi had collected a total of 200 brains and 12 spinal cords samples from patients in collaboration with J
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And 1912 at the Rockefeller Institute in New York City, Noguchi was working on a syphilis skin test, which could provide an additional diagnostic procedure to complement the Wassermann test in the detection of syphilis
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Noguchi published his manuscript, Serum Diagnosis of Syphilis, his most popular publication, assisting doctors and physicians in the diagnosis and treatment of syphilis
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Wrote his comprehensive monograph, Snake Venoms: An Investigation of Venomous Snakes with Special Reference to the Phenomena of Their Venoms, which contained several drawings and photographs of specimens
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Noguchi released a comprehensive monograph on snake venom, Snake Venoms: An Investigation of Venomous Snakes with Special Reference to the Phenomena of Their Venoms
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Wrote to about the accomplishment, "Everything is beautiful when it is still in a dream state, but when it becomes a reality it is no longer interesting to me
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The University of Pennsylvania awarded Hideyo Noguchi an honorary degree
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Wrote the chapter on venoms in William Osler and Thomas McCraes Modern Medicine
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Noguchi began working on refining it as it utilized serum reactions, which he was familiar from the course of his research of snake venom
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Noguchi was the first person in the United States to confirm the spirochete sixty days after its discovery
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To 1907 operated medical concentration camps in Africa to find a cure for sleeping sickness and blinded patients, and Louis Pasteur experimented on nine-year-old Joseph Meister without a medical license and was suspected
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Treponema pallidum was first identified as the cause of syphilis by Fritz Schaudinn and Erich Hoffmann
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Noguchi went to the Statens Serum Institute in Denmark and produced one of the first antiserums to treat the North American rattlesnake bite alongside Thorvald Madsen
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Noguchi started his research position, earning eight dollars a month, coming straight out of Flexner's pocket
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Noguchi arrived in Philadelphia
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Noguchi met Simon Flexner during his internship as his translator, being one of a few people who spoke English and Japanese at the Kitasato Institute
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Noguchi changed his first name to Hideyo after reading a novel by Japanese author Tsubouchi Shōyō about a college student whose character had the same name as him
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Left for Tokyo to receive formal training and prepare for his examination
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Sixteen year old Noguchi apprenticed with the same clinic as the doctor who had performed his surgery
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Noguchi entered Mitsuwa elementary school
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Born 1876-11-09.
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Japan introduced medical examination for doctors, a costly and time consuming process
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