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Christian René Marie Joseph, Viscount de Duve was a Nobel Prize-winning Belgian cytologist and biochemist. He made serendipitous discoveries of two cell organelles, peroxisomes and lysosomes, for which he shared the Nobel Prize in Physiology or Medicine in 1974 with Albert Claude and George E. Palade. In addition to peroxisome and lysosome, he invented scientific names such as autophagy, endocytos…
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science · Belgian biochemist and cytologist (1917–2013) · university teacher · biochemist · chemist · physician · physiologist · cell biologist · also Christian de Duve, Duve
Born 2 October 1917 · Died 4 May 2013 · Q234590
48 published statements · 0 followers
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Zonebourse: Christian de Duve
Le Soir: Gabriel Ringlet sur Christian de Duve: «On a très peu d’amis dans la vie. J’en ai perdu un très grand»
Gentside Découverte: Christian de Duve, ancien prix Nobel de médecine, est décédé par euthanasie
RTBF: Entretien exclusif avec Christian de Duve
RTL: Christian de Duve, le dernier prix Nobel belge, est décédé (revoir l'interview)
The Boston Globe: Christian de Duve, scientist and Nobel laureate; at 95
Died 2013-05-04.
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PBS: Faces of Science: Christian de Duve
RTBF: Quai des Belges : Christian de Duve, portrait de Nobel / Bande annonce
Awarded honorary doctor of the Université libre de Bruxelles (2010).
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Its name was further contracted to simply the de Duve Institute
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It was renamed the Christian de Duve Institute of Cellular Pathology
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Won E. B. Wilson Medal (1989).
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Awarded Foreign Member of the Royal Society (1988).
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And at Rockefeller in 1988, though he continued to conduct research
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Awarded honorary doctorate of the University of the Mediterranean - Aix Marseille II (1978).
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Awarded the Nobel Prize in Physiology or Medicine — for their discoveries concerning the structural and functional organization of the cell.
Awarded Nobel Prize in Physiology or Medicine (1974).
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Awarded honorary doctor of Paris Descartes University (1974).
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The same year he received his Nobel Prize, he founded the ICP, which would later be renamed the de Duve Institute
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Founded the International Institute of Cellular and Molecular Pathology in Brussels, eventually renamed the de Duve Institute in 2005
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Originally named the International Institute of Cellular and Molecular Pathology (ICP)
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Awarded Dr H.P. Heineken Prize for Biochemistry and Biophysics (1973).
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Awarded honorary doctor of the University Lille-II (1973).
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From the Royal Netherlands Academy of Arts and Sciences
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Awarded Honorary doctor of Leiden University (1970).
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The Catholic University of Leuven was contentiously split into two separate universities along linguistic lines
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Achieved the first large-scale preparation of peroxisomes, confirming that l-α hydroxyacid oxidase, d-amino acid oxidase, and catalase were all the unique enzymes of peroxisomes
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Awarded Canada Gairdner International Award (1967).
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And de Duve simultaneously headed the research laboratories at Leuven and at Rockefeller University, dividing his time between New York and Leuven
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Awarded Francqui Prize (1960).
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Found other enzymes (such as catalase and D-amino acid oxidase), that were similarly distributed in the cell fraction—and it was then thought that these were mitochondrial enzymes
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Detlev Bronk, the then president of the Rockfeller Institute (what is now Rockefeller University) of New York City, met him at Brussels and offered him professorship and a laboratory
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And the Nobel Prize for Physiology or Medicine in 1974
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Was invited to the Rockfeller Institute (now Rockefeller University)
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His team demonstrated similar cell fractions with same biochemical properties from the ciliated protozoan Tetrahymena pyriformis; thus, it was indicated that the particles were undescribed cell organelles unrelated to mi
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Peroxisome in 1966, and autophagy, endocytosis, and exocytosis in one instance at the Ciba Foundation Symposium on Lysosomes held in London during 12–14 February 1963, while he, "was in a word-coining mood
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De Duve named them "lysosomes" to reflect their digestive properties
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And formally published in 1966, creating the name peroxisomes for the organelles as they are involved in peroxidase reactions
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Experimentally demonstrated that glucagon did influence the production (and thus the uptake) of glucose
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Lilly upgraded its methods to eliminate the impurity
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Received a financial assistance as Rockefeller Foundation fellow and worked for six months with Carl and Gerti Cori at Washington University in St
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For which he worked on the purification of penicillin
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His family (von Duve) came from Hanover and settled in Belgium after the Battle of Waterloo.De Duve married Janine Herman on 30 September 1943.
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Joined research in chemistry, working on insulin and its role in diabetes mellitus
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As a hyperglycaemic (blood-sugar elevating) substance among the pancreatic extracts
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At age three, he and his family returned to Belgium
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Born 1917-10-02.
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